Lions vs. 49ers odds, NFC Championship Game picks, bets


Teams with differing postseason history will meet on Sunday in the 2024 NFC Championship Game with a trip to Super Bowl 58 on the line. The Lions will face the San Francisco 49ers in Santa Clara, where Detroit will seek its first-ever Super Bowl appearance. San Francisco is looking to earn an eighth Super Bowl appearance and is playing in its 19th conference championship game, most all-time. Detroit is the No. 3 seed in the 2024 NFL playoff bracket after a 12-5 regular season and postseason victories over Los Angeles and Tampa Bay. San Francisco is the No. 1 seed, playing at home at Levi's Stadium after a narrow win over the Green Bay Packers a week ago.

Kickoff is at 6:30 p.m. ET in Santa Clara. For this game, SportsLine consensus lists the 49ers as seven-point favorites, while the over/under, or total number of points Vegas thinks will be scored, is 51 in the latest Lions vs. 49ers odds. Before you make any Lions vs. 49ers picks, you need to see the NFL predictions and betting advice from SportsLine's advanced computer simulation model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the conference championship round of the 2024 NFL playoffs on an incredible 184-129 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-21 roll on top-rated picks since Week 7 of last season and nailed seven straight top-rated picks entering the 2024 NFL playoffs. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Lions vs. 49ers and just locked in its picks and NFL playoff predictions. You can head to SportsLine now to see the model's picks. Now, here are several NFL odds and betting lines for Lions vs. 49ers:

  • Lions vs. 49ers spread: 49ers -7
  • Lions vs. 49ers over/under: 51 points 
  • Lions vs. 49ers money line: 49ers -318, Lions +258 
  • DET: The Lions are 7-2 against the spread in road games 
  • SF: The 49ers are 3-6 against the spread in home games
  • Lions vs. 49ers picks: See picks at SportsLine
  • Lions vs. 49ers live stream: fubo (try for free)

Why the Lions can cover

Lions quarterback Jared Goff has thrown for 564 yards and three touchdowns without a turnover in two playoff games, averaging 8.1 yards per attempt and completing a league-leading 74.3% of passes. The Lions are scoring more than 27 points per game in two postseason contests, and that comes after a regular season in which Detroit was in the top five in points per game, points per drive, yards per game, yards per drive, yards per play, and first downs.

Goff is in total command of the passing game, ranking in the top four in passing yards (4,575), pass completions (407), passing touchdowns (30), and sack rate (4.72%) this season. He was also firmly in the top 10 in yards per attempt (7.6), completion rate (67.3%), and passer rating (97.9). The Lions turn lengthy drives into touchdowns at an impressive rate, ranking No. 3 in red zone efficiency (64.1%) during the regular season. With only 31 sacks allowed in 17 regular season games, Detroit also stays ahead of the chains and allows its playmakers to capitalize. See which team to pick here.

Why the 49ers can cover

The 49ers have a top-tier defense that ranked in the top three in points allowed this season. The 49ers outscored opponents by 10.9 points per game on the way to the No. 1 seed in the NFC playoff bracket and the offense fired on all cylinders in the process. The 49ers led the NFL with 2.70 points per offensive possession, ranking in the top three in points per game (28.9) and scoring percentage (45.3% of drives).

San Francisco was the league's most efficient team on a play-by-play basis, averaging 6.6 yards per snap, and was in the top two in total yards per game (398.4) and total yards per drive (37.8). The 49ers also finished atop the NFL in red zone efficiency, scoring touchdowns on 67.2% of trips inside the 20-yard line, and were in the top four in first downs (383) and third down efficiency (47.5%). Kyle Shanahan's team committed only 18 turnovers in 17 games while producing at a top-four level in both passing offense and rushing offense. See which team to pick here.

How to make Lions vs. 49ers picks

SportsLine's model is leaning Under the point total, with no pass-catcher projected to generate more than 85 receiving yards. The model also says one side of the spread hits in well over 50% of simulations. You can only see the model's pick at SportsLine.

So who wins Lions vs. 49ers in the 2024 NFC Championship Game, and which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the Lions vs. 49ers spread you need to jump on Sunday, all from the model that is up well over $7,000 for $100 players on top-rated NFL picks since its inception, and find out.